AstraZeneca commences NKTR-118 Phase III clinical program for opioid-induced constipation AstraZeneca today announced enrolment of the first individual in the Stage III clinical program for NKTR-118, an oral peripherally-performing opioid antagonist getting investigated for the treating opioid-induced constipation cialis women . The Phase III clinical program is made to investigate the basic safety and efficacy of NKTR-118 as a medication to alleviate opioid induced constipation, a common side-effect of prescription opioids when useful for chronic pain administration.
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